Summary Of Oedipus Rex Essays (1019 words) - Greek Mythology

Summary Of Oedipus Rex Prologue: The play opens with the citizens of Thebes gathering around the Theban palace. Oedipus the king exits the Theban palace. He inquires to a priest as to why his followers are praying and lamenting. The priest explains that they are praying to the gods to end the plague; which has struck their city. This plague had rendered crops useless, wasted all the pastures, and left woman sterile and unborn children dead. The priest begs for Oedipus help. Oedipus tells the priest that he feels the citys pain. He states the pain he endures is worse for he feels the pain of all the people of Thebes. Oedipus says that he has known of the plague for a while, and has searched the ends of his mind for an answer. He tries to ease the pain of his citizens and give them hope by telling them he has sent his brother-in-law, Creon to the oracle at Delphi. Creon appears bearing good news, the oracle knows the cause of the curse. He says that Thebes houses filth and only when this filth is banished will the plague be lifted. The filth is the murderer of the previous king, Laios. Oedipus asks Creon for the details of the kings death. Creon explains that Laios was killed as he left Thebes on a pilgrimage. He states that the only survivor said robbers killed the king. Oedipus asks why the murder was not investigated fully, and Creon explains that the Sphinx song and the problems of Thebes demanded attention first. Oedipus swears to find the killer of king Laios, not only for the citys sake but to ensure his own safety as well. Sardinha-2 Parodos : It is at this point in the play that we first meet the chorus. The chorus made up of Theban elders, expresses a sense of fear for what Oedipus might uncover. They proceed to describe the plague and the misfortunes that have fallen on the city. They also cry to the gods for their intervention. Scene I: Oedipus exits the palace and asks for the help of the citizens of Thebes in finding Laios killer. He declares that if the killer is among them he should come forward, and his sentence will be lessened. He decrees that anyone housing the truth shall be banished, and does not exclude himself from the punishment. The chorus suggests Oedipus seek the help of Teiresias, the blind prophet who can see the future. Oedipus states that he has already sent for Teiresias on the advice of Creon. When Teiresias arrives Oedipus informs him of the oracles statements and asks for his help. Teiresias says that he never should have come and asks to leave. Oedipus tells Teiresias that he will be an enemy to Thebes if he refuses to help. Once again Teiresias refuses. Oedipus is angered by the silence and lashes out at the prophet. Teiresias tells Oedipus to look within himself before placing blame on others. Oedipus declares that Teiresias is implicated in the murder of the king. Teiresias finally tells Oedipus you yourself are the pollution of this country. Teiresias says I say that you are the murderer whom you seek. These words enrage Oedipus, he calls Teiresias sightless, witless, and senseless. Oedipus charges Teiresias with fraud, and asks why a prophet could not solve the riddle of the Sphinx. Sardinha-3 Teiresias ends the scene with a riddle for Oedipus in which he states the identity of Laios murderer. The scene ends with an ode by the chorus, in which they reiterate these events of the scene. Scene II: The second scene opens with Creon speaking to the men of Thebes. He speaks unhappily of the accusations brought upon him by the king. The chorus attempts to explain the kings behavior by stating that the accusations were made in the moment of anger. Oedipus enters and upon seeing Creon continues his accusations. Creon pleads with Oedipus to believe in him. He explains that he is not after his throne. He asks Oedipus to go to the priestess at Delphi to see if he has quoted her correctly. He tells Oedipus that if he is found guilty of treason to sentence him to death. Oedipus does

Free Essays on Rent

The production I chose to critique for this paper was the Broadway show,â€Å"Rent†. â€Å"Rent† is a play about a group of young adults living their lives in New York City, and the obstacles they encounter. Basically the two main characters are Mark and Roger; they are roommates living in a not so glamorous apartment. Roger has A.I.D.S. and expresses much depression throughout the show. Mark is an ametur filmest, with high hopes for his carrer. He used to date Maureen, another main character, and their relationship toward one another is one of the many sub-plots to the show. The first chacter I chose to concentrate on is Roger, who in my opinion is the most intriguing character in the show. Like I mentioned earlier Roger has A.I.D.S., and is very depressed. Roger spends most of his time playing his guitar in his apartment; due to his illness he is unmotivated to leave his home. He knows his time left on this earth is limited, and his main objective throughout the show is to write a song that he will be remembered by. He is seen several times throughout the show, alone in the apartment, practicing and perfecting his song. His objective slightly changes when he meets another tenant of his apartment by the name of MiMi. He almost immediately falls in love with her, which gives him a new objective of trying to get her to be with him. The best scenes I can remember where Roger expressed his objective the best were the few scenes where Roger is seen working on his song. Basically Roger sits mid-stage with the spot light on him practicing his song. With his gu itar in hand and a soft sinceer voice, he almost pleeds to God to help him finish his song. As he strums on his guitar he sings a song about leaving something behind when he dies, meaning his song. This scene is very basic, nothing really special about it, yet its message is so clear and moving that the character actually comes to life on the stage. The beat of these songs, is very... Free Essays on Rent Free Essays on Rent The production I chose to critique for this paper was the Broadway show,â€Å"Rent†. â€Å"Rent† is a play about a group of young adults living their lives in New York City, and the obstacles they encounter. Basically the two main characters are Mark and Roger; they are roommates living in a not so glamorous apartment. Roger has A.I.D.S. and expresses much depression throughout the show. Mark is an ametur filmest, with high hopes for his carrer. He used to date Maureen, another main character, and their relationship toward one another is one of the many sub-plots to the show. The first chacter I chose to concentrate on is Roger, who in my opinion is the most intriguing character in the show. Like I mentioned earlier Roger has A.I.D.S., and is very depressed. Roger spends most of his time playing his guitar in his apartment; due to his illness he is unmotivated to leave his home. He knows his time left on this earth is limited, and his main objective throughout the show is to write a song that he will be remembered by. He is seen several times throughout the show, alone in the apartment, practicing and perfecting his song. His objective slightly changes when he meets another tenant of his apartment by the name of MiMi. He almost immediately falls in love with her, which gives him a new objective of trying to get her to be with him. The best scenes I can remember where Roger expressed his objective the best were the few scenes where Roger is seen working on his song. Basically Roger sits mid-stage with the spot light on him practicing his song. With his gu itar in hand and a soft sinceer voice, he almost pleeds to God to help him finish his song. As he strums on his guitar he sings a song about leaving something behind when he dies, meaning his song. This scene is very basic, nothing really special about it, yet its message is so clear and moving that the character actually comes to life on the stage. The beat of these songs, is very...

Springs Lab Report Example | Topics and Well Written Essays - 1000 words

Springs - Lab Report Example this experiment was to determine the key elements of Hooke’s law, which include, among others, the simple harmonic motions, the requirements of these harmonic motions, understanding Hooke’s law in a nutshell, attempting to verify Hooke’s law using a simple spring, to ascertain the relationship between the frequency and the period of a spring, to come up with the spring constant, and to determine the relationship between the mass, period, and force of a spring undergoing harmonic motion among others. The bottom line objective in this case is to be able to make comparisons of the measured periods of the vibration and the ideal ones as stated or calculated in the theory. Measuring the static behavior of a simple spring in this experiment was aimed at providing a basis of establishing the existing relationship between stretch and force. The spring constant, which is the force that a spring exerts on the object, in the opposite direction, when an object applies a force on the spring is what this experiment aimed at achieving. According to Hooke, the spring constant can be calculated from the expression F=- KX, where F is the force applied on the spring and X the distance this spring would move as a result of the force. In this experiment, a simple experiment involving a mass, a spring, and a meter rule were used to test this phenomenon (Knight, Brian and Stuart 13). The tables below show the results of the different measurements obtained as a result of adding different masses on a spring, while recording the various stretches that are realized. Concisely, the objective was to determine the influence of the mass on the stretch of the spring and the nature of relationship that exists between these tow variables. The above results give an impression of a near linear relationship between the mass and the stretch, but the trend changes significantly after a certain mass has been exceeded. From the theoretical point of view, the point where the relationship between

Nursing Essay Example | Topics and Well Written Essays - 1500 words

Nursing - Essay Example Nevertheless, nursing has much more as a whole that what it appears to be to the ordinary citizens. I will be exploring throughout this paper my nursing philosophy, which pertains to what I believe to be the principal feature of nursing. In so doing, I will explore how I view my role, responsibilities, as well as how I plan to deliver care to patients. To begin with, my nursing philosophy and beliefs are based on the following premises: knowledge, compassion/caring, time management, respect, privacy of patients and honesty. My motive of pursuing a nursing as a career is based on the seven-value system. Nursing, unlike other careers, is pursued with the aim of helping and caring for others. I strongly believe that the success of a nurse depends hugely on the knowledge and the ability to use the knowledge in the health care setting. Polifroni and Welch (1999) argue that a good nurse must know the diseases, as well as the disease processes. This implies that a nurse must be able to appl y the knowledge and skills gained from class to the place of work to ensure effectiveness. However, it is worth noting that merely passing exams does not mean that the nursing student will be able to apply the knowledge in the healthcare setting. ... According to Dahnke and Dreher (2011), a dutiful nurse must also be able to think holistically in anticipation of the needs of his or her patients. To do this, a nurse must be able to prioritize health care concerns within the patient’s personal diagnosis and the entire patients that the nurse is taking care of. Time management is highly critical since it ensures that all the pressing needs are attended to on time. A nurse who is poor in time management and organization cannot succeed in providing quality health care expected on time given the daily responsibilities and shifts. I also strongly believe that to be a successful nurse, one needs to be compassionate and caring. These are values, which were instilled in me during my upbringing as a child by my parents and relatives. In the nursing profession, one needs to have a sense of compassion and care for patients and their families. As I earlier indicated, nursing is a calling and entails caring and providing treatments to pa tients and their family members. As a nurse, one must have a sense of compassion and be caring because patients come with different complications and needs - some emotional while others are physical. Therefore, a nurse must be prepared to handle both the physical and emotional needs of patients, according to Dahnke and Dreher (2011). In fact, most nurses fear working with patients with complicated emotional needs. However, I came to discover that these patients are easy to work with as long as a nurse has the sense of compassion and care. It became apparent that once a close relationship and trust is built between the nurse and the patients such patients become very humble and easy to work with. This indicates the importance of empathy and compassion in nursing

Marketing Research Tools Paper wk 3 Essay Example | Topics and Well Written Essays - 1000 words

Marketing Research Tools Paper wk 3 - Essay Example On the other hand, research areas having ample and reliable data available require use of information extracted from secondary sources. According to nature of sources and research methodology, different tools are selected and used by researchers. All these tools have their own use, advantages and disadvantages. Therefore, it is important for researchers to ensure that research tools are selected that are suitable for the nature of research approach i.e. primary and secondary and research methodologies i.e. quantitative and qualitative. Primary research itself consists of data collection from original resources. Primary research can employ qualitative and quantitative research methodologies and there are various tools that can be used for this research approach. Usual tools used for this research includes surveys, interviews, direct observations, experimentations, and focus groups. These tools help in collecting data that is specific to the needs of researcher. Furthermore, researcher s can levy necessary controls on the research process to maintain the integrity of data collected and using it appropriately for the purpose of research (Baker, 2012). Hence, it is possible for researchers to ensure that data collected is valid and trustworthy along with being authentic and reliable. These research tools are usually time and cost consuming however due to direct relevance to the research purpose, it is preferred for areas of research that have not been explored earlier or to corroborate with existing studies (Onkvisit & Shaw, 2008). As far as secondary research is concerned, it is use of data that is already available from existing sources. The tools available for secondary research include information available on the internet, market research conducted by government and individual market research firms, data available on firms’ websites and stock exchange, information from public and private agencies, personal records and published print sources (peer-review ed papers, books and journals) (Baker, 2012). While using secondary data, it is important to ensure that the data is appropriate for the purpose of research. Relevance of data in terms of time period is another major issue that researchers need to take care of. However, sometimes use of secondary data is beneficial as it is readily available and relatively cheap (as the original research expenses have been already incurred). While performing primary and secondary research, quantitative and qualitative research methodologies can be used depending on the nature of research. While selecting a research methodology, the purpose of research and type of information required for the research is determined which further shapes the nature of research. In quantitative research, the usual tools used for primary research are surveys, financial figures produced by the entities themselves, experiments and numerical readings produced by them, statistical modeling and examination through stratificat ion and segmentation (Onkvisit & Shaw, 2008). These tools help in acquiring first hand information which is reliable, valid and objective yet expensive to acquire. For quantitative research to be performed through secondary sources, the tools used can be numeric modeling and statistical analysis. These tools are used to perform correlational analysis of data already available through print and electronic sources. Example of it can be examination of industry performance by performing statistical examination of market

Sickle Cell Disease: Causes, Effects and Treatment

Sickle Cell Disease: Causes, Effects and Treatment Abstract Sickle cell disease is a genetically inherited hematological (blood) disorder that results from a mutation in the beta globin gene that is responsible for the development of hemoglobin. Hemoglobin is the protein that delivers oxygen to the red blood cells throughout the body. In the disease, a mutated variant of normal hemoglobin generates an abnormal structure of the cells, leading to the development of symptoms. Sickle cell anemia and beta thalassemia are two common types of sickle diseases that are discussed in this review. The symptoms, complications, and therapies are also highlighted in the context of the pathophysiology of the disease. Sickle Cell Disease: An Overview Sickle cell disease is a genetically inherited blood disorder and it is characterized by an abnormal structure or production of hemoglobin. Hemoglobin is the protein in red blood cells that transports oxygen to cells throughout the body (National Institutes of Health, 2014). The disease results from a mutation in the beta globin gene causing a class of sickle diseases, such as sickle cell anemia and beta thalassemia (Thein, 2008). Together, they are often referred to as the beta hemoglobinopathies and present a range in disease severity (Thein, 2008). Beta globin is a protein that produces hemoglobin and the gene mutation in both diseases produces abnormal variants of hemoglobin in the blood. This results in either a predominance of abnormal hemoglobin molecules in red blood cells or an absence of normal hemoglobin, and thus, normal red blood cells (Edwards et al., 2005). There are a number of available therapies that manage sickle cell disease and the only curative treatment is hema topoietic cell transplantation. Pathophysiology of Sickle Cell Disease The National Institutes of Health reports that sickle cell disease is the most common inherited blood disorder in the United States and it affects 70,000 to 80,000 Americans (National Institutes of Health, 2014). It is estimated to occur in 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans (National Institutes of Health, 2014). The disease affects 30 million people worldwide and it is most common among people who have ancestors from Africa, Mediterranean countries, the Arabian Peninsula, India, parts of South America, Central America and the Caribbean (Khoury, Musallam, Mroueh, Abboud, 2011; National Institutes of Health, 2014). As it is an inherited disease, the sickle gene is presumed to have a genetic advantage in which it protects from the development of malaria infection (Stuart Nagel, 2004). There are many types of sickle diseases, such as sickle cell anemia and beta thalassemia. Sickle cell anemia is considered the most commonly occurring type of sickle c ell disease (National Institutes of Health, 2014). In sickle cell anemia, hemoglobin S replaces both beta-globin and the sixth amino acid is changed from glutamic acid to valine (National Institutes of Health, 2014; Rees Gibson, 2011). Sickle cell trait is not considered a disease and it is found in approximately 1 in 10 African Americans (Edwards et al., 2005). When both parents have the sickle cell trait, there is a one in four chance with each pregnancy that the child will have sickle cell anemia (Edwards, et al., 2005). Today, many health organizations offer newborn screenings that can determine if a child has either the disease or trait (National Institutes of Health, 2014). The development of the disease occurs due to the polymerization of deoxygenated hemoglobin S (Chirico Pialoux, 2012). The polymer formation modifies the normal red blood cell disc shape into a rigid, irregular-shaped, unstable cell and causes intravascular hemolysis, or rupture of the cells, to release hemoglobin into the plasma of the blood (Chirico Pialoux, 2012). The repeated polymerization leads to sticky blood cells (blood cell adhesion), obstruction of blood vessels (vasocclusion), and restriction of blood supply to tissues and organs in the body (ischemia) (Chirico Pialoux, 2012). Additionally, the endothelium and leukocyte, or white blood cells, are also found to play a role in disease mechanisms. Studies have found a connection between the endothelium, a thin layer of cells that line the interior surface of blood vessels, and sickled red blood cells (Stuart Nagel, 2004). The red blood cell receptors that are associated with cell adhesion are present in increased numbers on sickled immature red blood cells and mature sickle cells compared to normal red blood cells (Stuart Nagel, 2004). This finding demonstrates a structure-function abnormal activity that leads to coagulation on cell surfaces, leading to anemia (Stuart Nagel, 2004). Like cell adhesion, leukocytes have an impact in disease activity. White blood cells are found to be at an increased baseline in sickle cell disease, which serves as an independent risk factor for pulmonary and cardiac complications (Stuart Nagel, 2004). The size of the white blood cell, its rigidity, and adhesive characteristics are implicated in microvascular blood flow, vascular inflammation, and vasocclusion (Stuart Nagel, 2004). Clinical Symptoms of Sickle Cell Disease The clinical manifestation of sickle cell disease can lead to inflammatory responses and may result in acute chest syndrome, pulmonary hypertension, and stroke (Chirico Pialoux, 2012). People with sickle cell disease may also encounter several physical complications, such as delayed growth, fatigue, headaches, and cerebral vascular damage (Edwards et al., 2005). Acute chest syndrome is considered the second most common cause of hospital admissions and a leading cause of death in patients with sickle cell disease (Khoury, Musallam, Mroueh, Abboud, 2011). It involves the presence of a pulmonary infiltrate on a chest X-ray and the symptoms may include chest pain, a temperature of more than 38.5 degrees Celsius (101.3 degrees Fahrenheit), tachypnea (rapid breathing), wheezing or cough ((Khoury, Musallam, Mroueh, Abboud, 2011). The symptoms at clinical presentation vary with age as wheezing, cough, and fever are common in children 10 years or younger (Khoury, Musallam, Mroueh, Abboud, 2011). Pain in the arms and legs and shortness of breath are more commonly presented in adults with the disease (Khoury, Musallam, Mroueh, Abboud, 2011). It is believed that there are three mechanisms involved in acute lung injuries, which include infection, fat embolization (clotting) from bone marrow, and sequestration of sickled red blood cells (Khoury, Musallam, Mroueh, Abboud, 2011). People with sickle cell disease have an increased risk for developing infections, particularly pneumonia. Treatment for acute chest syndrome is primarily supportive and includes supplemental oxygen to keep the saturation above 92% (Khoury, Musallam, Mroueh, Abboud, 2011). Pain is considered the most frequent complication associated with the disease and acute chest syndrome stimulates this crisis (Edwards et al., 2005; Khoury, Musallam, Mroueh, Abboud, 2011). Repeated episodes of acute chest syndrome predispose patients to chronic pulmonary disease, such as pulmonary hypertension (Stuart Nagel , 2004). The occurrence of asthma is also associated with the increased incidence of acute chest syndrome, which is considered a comorbid condition found in people with sickle cell disease (Khoury, Musallam, Mroueh, Abboud, 2011). Beta Thalassemia Beta thalassemia is a common genetic blood disease that reduces hemoglobin production (National Institutes of Health, 2014). The hemoglobin gene mutation results in an unusually low level of beta-globin (National Institutes of Health, 2014). There are different levels of thalassemia based on the number of copies of beta thalassemia alleles or different copies of the same gene (Thein, 2008). The variety in alleles impacts the deficit in beta globin production, which, in turn, impacts disease severity (Thein, 2008). Carriers, for example, who have inherited a single copy of the beta thalassemia allele are clinically asymptomatic and may demonstrate mild anemia (Thein, 2008). Unlike a globin imbalance that is found in sickle cell anemia, variants of beta chains are broken down and result in ineffective red blood cell production in beta thalassemia (Thein, 2008). Physical complications involve cardiac and bone disease, bilirubin metabolism, and iron metabolism. Such symptoms may include jaundice and a predisposition to gallstones (Thein, 2008). Treatment for Sickle Cell Disease Several complications may emerge from sickle cell disease, whether it is in sickle cell anemia or in beta thalassemia. The purpose of therapies for sickle cell disease is to prevent and treat complications (Inati, Chabtini, Mounayar, Taher, 2009). The treatment of sickle cell disease is best achieved by decreasing the amount of hemoglobin S through the prevention of its production (Inati, Chabtini, Mounayar, Taher, 2009). People with severe sickle cell disease are treated with three validated therapies: hydroxyurea, transfusion and chelation therapy, and a hematopoietic or stem cell transplant (Inati, Chabtini, Mounayar, Taher, 2009). Hydroxyurea has been shown to be an effective form of treatment for children and adults with the disease. It has been demonstrated to reduce pain and acute chest syndromes, and it decreases the frequency of hospitalizations and the need for transfusions. This therapy has also been found to play a role in stroke prevention (Inati, Chabtini, Mounayar, Taher, 2009). At a molecular level, hydroxyurea reduces the adhesion of sickle red cells to endothelial cells. It also modulates endothelial cell activation and nitric oxide generation (Inati, Chabtini, Mounayar, Taher, 2009). Nitric oxide has been found to affect acute and chronic complications of sickle cell disease (Stuart Nagel, 2004). Nitric oxide, on a normal functioning level, induces relaxation of smooth muscle and dilation of blood vessels. In sickle cell disease, the bioavailability of nitric oxide is impaired, resulting in an imbalance between endothelial production and consumption (Stuart Nagel, 2004). The lungs are most affected by a reduction of nitric oxide and tend to constrict, which predisposes an individual to acute chest syndrome (Stuart Nagel, 2004). No adverse effects have been thus far reported on the usage of hydroxyurea and any toxicity is typically reversible (Inati, Chabtini, Mounayar, Taher, 2009). Transfusion therapy is currently considered a standard of care treatment for primary and secondary stroke prevention in children with sickle cell disease (Inati, Chabtini, Mounayar, Taher, 2009). It is used for short and long term management, preventing a first stroke in high-risk children as well as preventing against a recurrent stroke (Inati, Chabtini, Mounayar, Taher, 2009). Transfusions are also used for chronic and severe pain or in cases when patients with acute chest syndrome do not respond to hydroxyurea (Inati, Chabtini, Mounayar, Taher, 2009). Chelation therapy is used for patients who experience iron overload. Iron overload is a serious and inevitable outcome from receiving regular transfusion therapy (Inati, Chabtini, Mounayar, Taher, 2009). Unless treated, iron overload may result in severe organ damage and other life threatening complications and this treatment mediates this by removing excess metals from the body (Inati, Chabtini, Mounayar, Taher, 2009). While hydroxyurea, tranfusions, and chelation therapy aim to prevent and treat complications, they do not cure sickle cell disease (Inati, Chabtini, Mounayar, Taher, 2009). The currently available curative treatment is a stem cell transplant. A transplant is indicated in those patients who experience complications, such as recurrent severe pain, acute chest syndrome, and stroke (Inati, Chabtini, Mounayar, Taher, 2009). Only one-third of affected children meet the criteria for a stem cell transplant as it is an aggressive and serious procedure (Inati, Chabtini, Mounayar, Taher, 2009). The goal of a stem cell transplant is to replace the host’s marrow with normal cells, resulting in a new immune system (Stuart Nagel, 2004). Studies on stem cell transplant as a curative option for patients with severe sickle cell disease are demonstrating mean overall survival and event-free survival rates between 95 and 85% (Inati, Chabtini, Mounayar, Taher, 2009). Significant advancements have been made for pediatric patients who have beta thalassemia and were treated with a stem cell transplant. Over the last three decades, disease-free survival rates have exceeded 80% in patients who received transplants from biologically compatible family donors (Mehta Faulkner, 2013). Sickle cell disease is a genetically inherited blood disorder that is primarily diagnosed in people who have ancestors from Africa, Mediterranean countries, the Arabian Peninsula, India, parts of South America, Central America and the Caribbean (Khoury, Musallam, Mroueh, Abboud, 2011; National Institutes of Health, 2014). The disease results by a mutation in the gene that creates beta globin, which is the protein that is responsible for producing hemoglobin. Hemoglobin is the protein in red blood cells that transports oxygen to the body’s organs and tissues. When the mutation occurs, a hemoglobin variant is produced, resulting in a structural and functional change in the red blood cells. Several physical complications emerge in both children and adults who have the disease. These may include, but not limited to, pain, acute chest syndrome, cerebral and vascular damage (Edwards et al., 2005). There are three primary therapies for managing and/or treating the disease. These inc lude the drug, hydroxyurea, transfusion and chelation therapy, and hematopoietic cell transplantation (Inati, Chabtini, Mounayar, Taher, 2009). More research is underway in the development of additional treatment options, such as gene therapy and clinical trials are exploring this possibility. References Chirico, E. N., Pialoux, V. (2012). Role of oxidative stress in the pathogenesis of sickle cell disease. International Union of Biochemistry and Molecular Biology Life, 64 (1), 72-80. Edwards, C. L., Scales, M. T., Loughlin, C., Bennett, G. G., Harris-Peterson, S., De Castro, L. M., Whitworth, E., Abrams, M., Feliu, M., Johnson, S., Wood, M., Harrison, O., Killough, A. (2005). A brief review of the pathophysiology, associated pain, and psychosocial issues in sickle cell disease. International Journal of Behavioral Medicine, 12 (3), 171-179. Inati, A., Chabtini, L., Mounayar, M., Taher, A. (2009). Current understanding in the management of sickle cell disease. Hemoglobin, 33 (S1), S107-S115. Khoury, R. A., Musallam, K. M., Mroueh, S., Abboud, M. R. (2011). Pulmonary complications of sickle cell disease. Hemoglobin, 35 (5-6), 625-635. Mehta, P. A., Faulkner, L. B. (2013). Hematopoietic cell transplantation for thalassemia: a global perspective BMT tandem meeting 2013. Biology of Blood and Marrow Transplantation, 19, S70-S73. National Institutes of Health (2014). Genetics home reference: beta thalassemia. U.S. Department of Health and Human Services, Retrieved from http://www.ghr.nlm.nih.gov/condition/beta-thalassemia. National Institutes of Health (2014). Genetics home reference: sickle cell disease. U.S. Department of Health and Human Services, Retrieved from www.ghr.nlm.nih.gov/condition/sickle-cell-disease. Rees, D. C., Gibson, J. S. (2011). Biomarker in sickle cell disease. British Journal of Haematology, 156, 433-445. Stuart, M. J., Nagel, R. L. (2004). Sickle-cell disease. Lancet, 364, 1343-1360. Thein, S. L. (2008). Genetic modifiers of the ÃŽ ²-haemoglobinopathies. British Journal of Haematology, 141, 357-366.

A Knowledge Entry System for Subject Matter Experts :: essays research papers

The High Performance Knowledge Bases (HPKB) project demonstrated that the teams of knowledge engineers working together could create knowledge bases (KBs) roughly at the rate of 10K axioms/year for a pre-specified task and evaluation criteria. The HPKB effort showed that it is possible to create KBs by reusing the content of knowledge libraries, and it demonstrated reuse rates ranging from 25% to 100%, depending on the application and the knowledge engineer. It was acknowledged that the ability of a subject matter expert (SME) to directly enter knowledge is essential to improve the KB construction rates. The SRI team is developing a system for direct knowledge entry by SMEs as an integrated team of technology developers. The SRI team includes Boeing, Information Sciences Institute (ISI) at University of Southern California, Northwestern University, Pacific Sierra Research (PSR), Stanford University, University of Massachusetts at Amherst, University of Texas at Austin, and University of West Florida. Knowledge Systems Laboratory at Stanford, Pragati Systems, and Massachusetts Insititute of Technology joined the team after the contract award. The claim of this effort is that SMEs, unassisted by AI technologists, can assemble models of mechanisms and processes from components. These models are both declarative and executable, so questions about the mechanisms and processes can be answered by conventional inference methods (for example, theorem proving and taxonomic inference) and by various task-specific methods (for example, simulation, analogical reasoning, and problem-solving methods). A related claim is that relatively few components, perhaps a few thousand, are sufficient for SMEs to assemble models of virtually any mechanism or process. We claim that these components are independent of domain, and that assembly from components instantiated to a domain is a natural way for SMEs to create KB content. The research in this project exploits and extends previous work in the HPKB project, as well as work in process description languages, qualitative physics, systems dynamics, and simulation. One scientific innovation, and the principal extension to Cyc and the "HPKB standard" of knowledge bases, is the idea of declarative and executable models (DEMs) assembled from components. The declarative aspect of DEMs supports conventional inference, whereas the executable aspect supports reasoning by simulation. For example, the declarative part of a model of aerosols is sufficient to answer questions like, "Will a 5-micron filter afford protection against this aerosol?" while the executable part is necessary to model the dispersal pattern of the aerosol.

Graduate Studies Challenges And Strategies Essay

There are many challenges that a student will face while completing graduate study. One challenge is to choose the title of the thesis or dissertation. Another challenge is to have more than enough money to complete graduate study. A third challenge is to pass the thesis or dissertation defense. The other challenges will surely pale in comparison with these three uphill challenges. They will surely try to break the student’s strong resolve to finish run the graduate study race. There are many strategies that they can use to address these challenges. We can easily list very effective ways the students can use to address the challenge to choose the title of the thesis or dissertation. We can easily enumerate very worthy ways the students can use to address the challenge to have more than enough money to complete the financially draining graduate study. We can easily jot down very efficient traditions the students can use to address the challenge to cross the finish line in the thesis or dissertation defense race(Palmer, 2006). BODY We can easily list very effective ways the students can use to address the challenge to choose the title of the thesis or dissertation. First, the student can research the Graduate School library copies to have several clues on how the titles of the thesis or dissertation were crafted. Second, the student can research other resources to accomplish this daunting task. Third, the student can ask the tutor or professor to guide the student along this disheartening graduate study phase. Lastly, the student can give up. Further, the student must use all the ways listed above to complete his graduate study mission to address the challenge to choose the title of the thesis or dissertation. The Graduate School library’s store of passed thesis or dissertations will surely guide the student on the different chapters of the thesis or dissertation. These accomplished library references will clearly show the long and narrow path that the students must also thread in order to get the tutor’s or graduate school professor’s nod in terms of the thesis or dissertation title. All these books generally will have a common denominator that will shed the light on the most likely thesis or dissertation title that the tutor or graduate school professor will favor(Timmerman,2006). We can easily enumerate very worthy ways the students can use to address the challenge to have more than enough money to complete the financially draining graduate study. First, the student can borrow money pay for the daily graduate school expenses. Second, the student can find work to pay the inescapable expenses to wiggle through the complex and overwhelming graduate study. Third, the student can seek scholarships to help defray the money needed to keep in pace with his graduate study mates. Fourth, the student can raise the flag of defeat. The student can pick one of the four worthy ways to address the challenge to have more than enough money to complete the financially draining graduate study. One student can easily find money if he or she chooses to borrow from moneyed relatives, banks, or other money lenders as compared to the other three strategies. Another student’s choice to gather enough finances by finding a job to defray his graduate school expenses could be his or her easiest option as contrasted with the other choices enumerated in the prior paragraph. The academically gifted student can apply for scholarships in order to pay for the expenses of accomplishing the academic requirements of his or her field of choice(Peterson,2005). We can easily jot down very efficient traditions the students can use to address the challenge to cross the finish line in the thesis or dissertation defense race. First, the student can literally ask the aid of his or her tutor or graduate school mentor. Second, the student can seek the help of someone who is an expert in the complex science of thesis or dissertation defense. Third, the student could use secondary resources to successful answer the defense panels’ barrage of questions with flying colors. Lastly, the student can loudly proclaim I Quit. Further, one student could find that the most comfortable tradition is to literally ask the aid of his or her tutor or graduate school mentor. Many graduate school students of different intelligences find this step a must. Another student would be most at home implementing the traditional way of seeking the help of someone who is an expert in the complex science of thesis or dissertation defense. The expert will lessen the student’s time needed to list the possible questions and to prepare the most academically correct answers to each questions during the much awaited graduate school defense. All the students must incorporate the traditional use of secondary resources to successful answer the defense panels’ barrage of questions with flying colors. This choice will undoubtedly complement the other traditions discussed(Glatthorn & Joyner,2005). CONCLUSION There are many strategies that the students can use to address the many challenges that they will face while completing graduate study to avoid giving up their academic dream. The student must use all the ways listed above to complete his graduate study mission to address the challenge to choose the title of the thesis or dissertation. The student can pick the one of the four worthy ways to address the challenge to have more than enough money to complete the financially draining graduate study. The students can use the best tradition that they feel most comfortable to address the challenge to cross the finish line in the thesis or dissertation defense race. Conclusively, there are many strategies that the students can use to address the many challenges that they will face while completing graduate study to avoid giving up their academic dream. REFERENCES: Glatthorn, A. , Joyner, R. , (2005), Writing the Winning Thesis or Dissertation: A Step –by -Step Guide, N. Y. , Corwin Press Palmer, W. , (2006), Dissertations on Subjects Relating to the â€Å"Orthodox† or â€Å"Eastern Catholic† Communion, Harvard, Harvard University Press Peterson, T. , (2005). Peterson’s Four Year Colleges, N. Y. , Peterson’s Publishing Timmerman, C. , (2006). The Everything Pencil Puzzles Book: Sharpen Up Your Puzzle – Solving Skills, N. Y. , Everything Books,

Practice Decision Making Essay example

Practice Decision Making Essay example Practice Decision Making Essay example 1-Mann Gulch: Miscalculation: An accurate landing zone. Failed to evaluating the risk. Teamwork issues. Briefing problems. Follow Order problem Open: Dodge was not open to his crew that cause misunderstood in many stuations. Communication problems: No maps, Disconnect Radios, Poor communicate between the leader and the firefighters. Timing Issues: Dodge showed disorganized time consuming Group Organization. No discipline Lack of knowledge: lack the concept of escape fire. Lack of Training. Lack of experience. Crew had a panic reaction Ineffective or wrong decision making under stress. No rescue plan. No escape route. Storm king mountain: Disorganization of coordination between the Blm and USFS. Bureaucracy problems. Briefing the task info problem. Multiple leadership in many team cause confusions for the firefighters, it suppose for Blanco to identify himself as the IC. Communication: each team use different frequency for their Radio. Fire behavior: including the weather, fuel, the terrain. Follow order problem: some resistance from Mackey’s jumpers on the fire line that Mackey and Blanco want to build. Lack of resource. The can-do attitude. Training required (physical and knowledge) Ability to make decision . 2- As a leader he did practice very poor leadership. He wasn’t open to his crew, never invite them to his house to build a good teamwork and never tried to k now their hidden talented. He even didn’t know the names of all the men in his crew. Dodge: lack of knowledge of many firefighter concepts and standards .His experience within the 8 years he had was not enough and for sure he need more training. He missed the 2 weeks training that summer before the tragedy. He was unable to make decision under stress or have the ability to make his crew follow his order. Didn’t take or make his crew act seriously. Dodge Mistakes: Dodge left his crew twice while they are in the theater zone and that cause confusion beside crew lack of instructions and made the crew split to 2 units. Late react when faces issues and communicating. Ha had problem with giving orders , making decisions . No escape route plan, Failed to apply back fire concept. He didn’t share the same vision with his crew and that cause the tragedy. Mackey and Blanco both demonstrate social , interpersonal skills that Dodge lack beside more physical fitness and more abilities using tools. Blanco mistake as a leader when he didn’t evaluate the risk well and depend on his judgment when didn’t thought that he will need smokejumpers and that’s why he never met mackey for briefing . He just instruct him by Radio and gave him some instructions without full details about the fuel behavior , the weather and the terrain . He never present him self as leader and that cause misunderstanding with all the ground teams. Mackeu didn’t follow the standards and the policy when he made decisions and that cause disagree by the smokejumpers. As a leader you have to use judgment but it should follow the policy and the standards. 3- The teamwork aspect was available in Mackey group, All of his group show respect to him and that because of his knowledge, skills and the good leadership features

Practice Decision Making Essay example

Practice Decision Making Essay example Practice Decision Making Essay example 1-Mann Gulch: Miscalculation: An accurate landing zone. Failed to evaluating the risk. Teamwork issues. Briefing problems. Follow Order problem Open: Dodge was not open to his crew that cause misunderstood in many stuations. Communication problems: No maps, Disconnect Radios, Poor communicate between the leader and the firefighters. Timing Issues: Dodge showed disorganized time consuming Group Organization. No discipline Lack of knowledge: lack the concept of escape fire. Lack of Training. Lack of experience. Crew had a panic reaction Ineffective or wrong decision making under stress. No rescue plan. No escape route. Storm king mountain: Disorganization of coordination between the Blm and USFS. Bureaucracy problems. Briefing the task info problem. Multiple leadership in many team cause confusions for the firefighters, it suppose for Blanco to identify himself as the IC. Communication: each team use different frequency for their Radio. Fire behavior: including the weather, fuel, the terrain. Follow order problem: some resistance from Mackey’s jumpers on the fire line that Mackey and Blanco want to build. Lack of resource. The can-do attitude. Training required (physical and knowledge) Ability to make decision . 2- As a leader he did practice very poor leadership. He wasn’t open to his crew, never invite them to his house to build a good teamwork and never tried to k now their hidden talented. He even didn’t know the names of all the men in his crew. Dodge: lack of knowledge of many firefighter concepts and standards .His experience within the 8 years he had was not enough and for sure he need more training. He missed the 2 weeks training that summer before the tragedy. He was unable to make decision under stress or have the ability to make his crew follow his order. Didn’t take or make his crew act seriously. Dodge Mistakes: Dodge left his crew twice while they are in the theater zone and that cause confusion beside crew lack of instructions and made the crew split to 2 units. Late react when faces issues and communicating. Ha had problem with giving orders , making decisions . No escape route plan, Failed to apply back fire concept. He didn’t share the same vision with his crew and that cause the tragedy. Mackey and Blanco both demonstrate social , interpersonal skills that Dodge lack beside more physical fitness and more abilities using tools. Blanco mistake as a leader when he didn’t evaluate the risk well and depend on his judgment when didn’t thought that he will need smokejumpers and that’s why he never met mackey for briefing . He just instruct him by Radio and gave him some instructions without full details about the fuel behavior , the weather and the terrain . He never present him self as leader and that cause misunderstanding with all the ground teams. Mackeu didn’t follow the standards and the policy when he made decisions and that cause disagree by the smokejumpers. As a leader you have to use judgment but it should follow the policy and the standards. 3- The teamwork aspect was available in Mackey group, All of his group show respect to him and that because of his knowledge, skills and the good leadership features

Best Entry Mode Into the German Wine Market Essays

Best Entry Mode Into the German Wine Market Essays Best Entry Mode Into the German Wine Market Essay Best Entry Mode Into the German Wine Market Essay Essay Topic: The Man Of Mode There are opportunities in the German market for Goldenrods such as demand for non-alcoholic beverages and organic wines. At the same time there are challenges in the German market such as stringent overspent regulation, high competition and slow growth of the market. The advantages and disadvantages of the three entry modes- exporting, acquisition and joint venture are investigated and a recommendation is made on the best suited entry mode for Goldenrods. The first section of the report gives a brief introduction about the company and its background. In the second section, a detailed internal and external analysis of the company is done to understand its strengths and weaknesses, and the opportunities and threats that the company is likely to face in the German wine market. In the third section, three entry modes that are best suited for Goldenrods in its entry into the German wine market is analyses and the best entry mode is suggested. The report is concluded in the final section. 2. 0 Company Profile : Goldenrods Goldenrods is the third largest producer of wine in Australia, generating 5. 0% of the markets volume. The company produces, sells and distributes wine and beer and has its market in 98 countries around the world. The company operates in Australia, Asia Pacific, U. S, Europe, the Middle East and Africa. The company has its headquarters in Bill, Australia and employs around 5,900 people. Its products are supplied to around 29,000 customers including wholesalers, importers, hotels, bottle shops and restaurants. Goldenro ds revenues during the financial year 2008 was recorded to be A$ 2,900 million with a net profit of A$ 5,50 million. Strong manufacturing capabilities helps the company to achieve economies of scale, and enable it to maintain control over quality and respond quickly to changes in demand. Focus on product innovation Goldenrods has a strong focus on product innovation and believes that it is a ajar driver of business success. In response to the growing consumer trend for lifestyle alternatives (Denominator, 2008), Goldenrods launched a new range drinks with low carbohydrates, low calorie, reduces alcohol and reduced preservatives. The company also demonstrates innovation in its packaging style, packaging materials and wine bottles. A strong focus on product innovation allows Goldenrods to stay ahead of competition in the market. 3. 2 Weaknesses Inefficient operations The average inventory and receivables turnovers of Goldenrods were lower than its competitors during the five year period 2004-2008. The average inventory and average receivable turnover of the group stood at 2. 3% and 5. 5%, respectively, during 2004-2008, significantly lower than its competitors like De Portola and Misalliances Wine Pity. Ltd (Denominator, 2008). The lower inventory and receivables turnovers of endoscopes Annihilate ten lower productivity Ana operational Inclemency AT ten company. Further, due to lower inventory and receivable ratios, Goldenrods would require a higher working capital, which may limit the groups growth prospects. Goldenrods would have to thoroughly investigate how and why the productivity less ND would have to immediately eliminate or improve inefficient operations and units. If not resolved immediately, this can have a negative impact on its operations in all of the different markets around the world. Weak revenue per employee Fosters has recorded weak revenue per employee in the recent past. During 2004-2008, the groups average revenue per employee was A$313,653, significantly lower when compared to its competitors like De Portola and Misalliances Wine Pity. Ltd (Denominator, 2008). The weak revenue per employee of the group indicates its weaker productivity and operational inefficie ncy when compared to its competitors. This also have an impact on the net profits of the company and can hamper its growth if not resolves immediately. Efficient ways have to be devised in order to reduce operational wastage of money and to increase productivity. If these matters are not looked into immediately, then it can hamper the growth and the net profits from its entire markets spread around the world. 3. 3 Opportunities Increasing concern for health and wellness The average German consumer is getting old and there is an increased concern for health and wellness Nonsense, 2008). According to Remuneration market (2009) port, German alcohol consumption is declining in general as consumers are seeking to cut down alcohol intake due to health concerns. The ageing population will further worsen the situation, with older consumers typically consuming less alcohol (Remuneration, 2009). Still light grape wine, which is dominant in the market, is expected to particularly suffer, with consumers less likely to serve such wine with everyday meals (Denominator, 2008). Health and wellness is a growing sector in Germany and there is a growing trend for health and wellness products Nonsense, 2008). Though it might seem like a big wreath to Goldenrods, infant this is a great opportunity for the company. Goldenrods has already launched a range of products that are low in calorie content and alcohol content. Goldenrods would find a good market in Germany for its healthy wine segment. In addition to this, non-alcoholic beverages are becoming an important segment for wine and beverage distributors around the world (Denominator, 2008). As Goldenrods already distributes non-alcoholic beverages, it could boost its revenue growth by expanding further its portfolio of non-alcoholic beverage in the German market. Growing popularity AT Rose Ana organic well There is a growing trend towards rose wines in Germany and this is forecasted to remain popular within the German market and boost sales (Remuneration, 2009). Another product area that saw a good performance was low alcohol sparkling wine, which benefited from the health trend (Denominator, 2008). There is also a growing preference for organic wine in Germany and this is in line with the good overall development of organic products in Germany Owes, 2006). An increasing number of companies in the German wine industry have launched organic line extensions or new organic brands Owes, 2006; Remuneration,2009). There is a great opportunity for Goldenrods in the German market as it can find a good market for its already existing rose wines. Goldenrods can also diversify its rose wine by offering rose variants that suit the local German consumers taste. Goldenrods can also expand its portfolio and launch a new line of organic wines as there is a great opportunity to boost its revenue through sales in this segment. The geographic spread of Goldenrods would definitely help the company in sourcing good quality organic raw materials.

Colonialism in Southeast Asia and the Austral and Pacific Realms Essay

Colonialism in Southeast Asia and the Austral and Pacific Realms - Essay Example However, though the Philippines became subjected to another power, they still maintained some of their native belief systems. Colonization of the Philippine realm was due to its potential in commercial success with other countries. During the 18th century, the Spanish population was significantly less but soon the population started expanding. Intermarriage of the Spanish and the Philippines led to the growth of a very strong community that became the most powerful politically and economically (McCoy, 2001). A consequent growth of the Spanish community in Philippine later took over the Philippine realm. Spanish colonization of the Philippine realm did not face confrontation by indigenous states supported by aristocracies, bureaucracies, or religious organization contrast to other European colonizers elsewhere in Southeast Asia. In addition, the Spanish rule over the Philippines defined the modern state of the Philippines in matters concerning the social, religious, and ideological underpinnings. The Spanish rule over the Philippines had less impact to them economically. However, there was a considerable impact on the people politically and religiously. To have full control of the Philippine realm, the Spaniards gradually abolished hereditary nobility and dignity, limited power to Philippine chiefs, encouraged slavery and subsequently secured themselves high aristocratic positions in the state. Since Philippine had a history of economical flourish, the Spaniards took this as an opportunity to excel, expand, and uplift their country’s economic status (Lockard, 2006). They used water to transport silver, gold, and other materials of exchange to Europe where it graced the lives of the European elite. Philippine consequently turned to a regional trading area in Southeast Asia. The key reason that enabled the Spaniards to colonize Philippine was the close relationship the state had with the church. Spain being a Christian realm wanted to convert

Peer review suggestions Essay Example | Topics and Well Written Essays - 250 words

Peer review suggestions - Essay Example Thus, all people require effective care and treatment. However, treatment may be hindered by various factors. One of the major factors is religion. The world has more than a dozen religions with each having different perception and approaches to health. Therefore, nurses need to understand the religious views concerning health before attending to patients. Among the main religious groups in the world are Christianity and Buddhism. Christianity is one of the oldest religions in the world with over 30% of the world’s population being Christians. Christians believe in God and His son Jesus Christ. Christianity has evolved gradually into two major groups; Catholicism and Protestants. However, the beliefs of the two groups are similar despite the differences in worship. Christian views resonate in healthcare and has a direct impact on the health care system. The Christian worldview can be better exposed through the worldview questions. Christians believe that the prime reality is that God exists and omnipresent, omnipotent and omniscient. God has the companionship of the Holy Spirit and the Son, Jesus Christ. All creatures came into being from his will and power; thus, all creatures are obligated to bow and worship him at all times (Shelly & Miller, 2009). Christians believe that the omnipotence of God is enough to heal them of any illnesses. Hence, Christianity has a direct impact on the nursing practice. The holy Bible stipulates that God created the world and everything in it. He created a complex system with a variety of creatures, many of which scientist have not named yet. However, humans have the power to influence the world around with aspects such as pollution and deforestation. God separated us from the sea and put living creatures in both masses. It follows that God controls the world. The orderly nature of the world, ecosystems, and natural environment prove that they must have